首页> 外国专利> human il-13 specific binding member, isolated antibody vh and vl domains, composition, isolated nucleic acid, host cell, methods for producing an antibody specific vh or vl domain or binding domain, a human il-13 specific antibody antigen, a specific binding member that binds human il-13, use of a specific binding member, and method of treating a disordered disease

human il-13 specific binding member, isolated antibody vh and vl domains, composition, isolated nucleic acid, host cell, methods for producing an antibody specific vh or vl domain or binding domain, a human il-13 specific antibody antigen, a specific binding member that binds human il-13, use of a specific binding member, and method of treating a disordered disease

机译:人il-13特异性结合成员,分离的抗体vh和vl结构域,组成,分离的核酸,宿主细胞,产生抗体特异性vh或vl结构域或结合结构域的方法,人il-13特异性抗体抗原,特异性结合结合人il-13的成员,特异性结合成员的使用以及治疗疾病的方法

摘要

"SPECIFIC LINK MEMBER ISOLATED FOR HUMAN IL-13, ISOLATED ANTIBODY VH AND VL DOMAINS ISOLATED, COMPOSITION, NUCLEIC ACID, HOST CELL, METHODS TO PRODUCE A LYMPHONOMIC DYNOMOUS OR LIFECON DYNOMOUS MEMBER ANTIGEN SPECIFIC ANTIBODY FOR HUMAN IL-13, A SPECIFIC CONNECTION MEMBER CONNECTING IL-13 HUMAN, USE OF A SPECIFIC CONNECTION MEMBER, AND METHOD OF TREATING A DISEASE OR DISORDER ". Specific binding members, in particular human anti-IL-13 antibody molecules and especially those that neutralize IL-13 activity. Methods for using anti-IL-13 antibody molecules in the diagnosis or treatment of IL-13 related disorders including asthma, atopic dermatitis, allergic rhinitis, fibrosis, inflammatory bowel disease, and Hodgkin's lymphoma.
机译:“为人类IL-13分离的特定连接成员,分离的抗体VH和VL域,组成,核酸,宿主细胞,产生淋巴瘤或人乳腺瘤的双抗原特异性细菌连接的方法,人类IL-13连接IL-13人,使用特定的连接构件以及治疗疾病或疾病的方法”。特异性结合成员,特别是人抗IL-13抗体分子,尤其是中和IL-13活性的成员。使用抗IL-13抗体分子诊断或治疗与IL-13相关的疾病的方法,这些疾病包括哮喘,特应性皮炎,过敏性鼻炎,纤维化,炎性肠病和霍奇金淋巴瘤。

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