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Pyrroloindoles, pyridoindoles and azepinoindoles as 5-HT2C agonists and their use

机译:吡咯并吲哚,吡啶并吲哚和氮杂吲哚作为5-HT2C激动剂及其用途

摘要

In the present invention, there are disclosed indole derivatives of the general formula I, in which n is 1, 2 or 3; and pharmaceutically acceptable salts and forms of these compounds designated as medicament precursors. Disclosed is also the use of the above-described compounds in therapy, particularly for the treatment of disorders of the central nervous system; damage to the central nervous system; cardiovascular disorders; gastrointestinal disorders, diabetes insipidus, and sleep apnea, and particularly for the treatment of obesity.
机译:在本发明中,公开了通式I的吲哚衍生物,其中n为1、2或3; n为1、2或3。以及这些化合物的可药用盐和形式,称为药物前体。还公开了上述化合物在治疗中的用途,特别是在中枢神经系统疾病的治疗中的用途。损害中枢神经系统;心血管疾病;胃肠道疾病,尿崩症和睡眠呼吸暂停,尤其是用于治疗肥胖症。

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