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ISOLATION, CHARACTERIZATION, AND USE OF THE HUMAN .BETA. SUBUNIT OF THE HIGH AFFINITY RECEPTOR FOR IMMUNOGLOBULIN E
ISOLATION, CHARACTERIZATION, AND USE OF THE HUMAN .BETA. SUBUNIT OF THE HIGH AFFINITY RECEPTOR FOR IMMUNOGLOBULIN E
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机译:人类.BETA的隔离,表征和使用。免疫球蛋白E高亲和力受体的亚基
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摘要
The present invention relates to nucleic acid sequences encoding amino acidsequences of the .alpha., .beta., and .gamma. subunits of thehigh affinity receptor for immunoglobulin E, and for amino acid sequences ofthe subunits. The invention further relates to amethod of producing the receptor by expressing cDNA for its .alpha., .beta.,and .gamma. subunits in a host cell simultaneously. Aspects of theinvention are methods and compositions to produce the human beta subunit, aswell as to inhibit its function, thereby treating orpreventing allergic reactions.
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