METHOD FOR SELECTING FEMALE PATIENTS WITH THE SYNDROME OF 'EMPTY' FOLLICLES FOR CARRYING OUT ECF AND ET PROGRAM WITH DONOR OOCYTES

摘要

FIELD: medicine, gynecology, reproductology.;SUBSTANCE: it is necessary to determine the content follicle-stimulating hormone (FSH) in follicular liquid in female patients with the syndrome of "empty" follicles (SEF), insulin-like growth factor (IGF-1) and human chorionic gonadotropin (hCG) to calculate differential value (DV) by the following formula: DV=exp(IV)/1+expIV), where IV - intermediate variable calculated by the following formula: IV=1.821+1×FSH-0.18×IGF-1+0.136×hCG, Exp - exponential function and at DV being below 0.5 the development of SEF is of absolute nature and a female patient should be recommended to have donation of oocytes, at DV being above 0.5 the development of SEF is of sporadic character and a patient should be recommended to undergo repeated curative ECF cycles. The innovation enables to elaborate the method for predicting the procedure of extracorporal fertilization and embryo transfer.;EFFECT: higher efficiency.;3 ex, 3 tbl