Chimeric protein containing proteinase cisteinica hepatica Fasciola fused with core protein of hepatitis bo ubiquitin; Plants expressing said protein; and its use as a vaccine.

摘要

Particle nucleinic acid encoding the chimeric protein under the control of the constitutive CaMV 35S promoter and whose characteristic is that the sequence encoding the chimeric protein consists of one of the following sequences: - a nucleotide sequence encoding the amino acid sequence domain catalyst of cysteine ​​proteinase liver, fused fascioliasis with a sequence encoding the Core protein HBc, - a nucleotide sequence encoding the amino acid sequence domain leader cysteine ​​proteinase liver, fused fascioliasis with a sequence encoding the Core protein HBc, - a nucleotide sequence encoding the amino acid sequence of the catalytic domain of the cysteine ​​proteinase liver, fascioliasis fused with a sequence encoding HBc Core protein and glycine residues, or - a nucleotide sequence encoding the amino acid sequence of domi nio the catalytic cysteine ​​proteinase liver, fascioliasis fused with a nucleotide sequence coding ubiquitin.