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Methods of modulating heme oxygenase-1 expression and treating heme oxygenase-1 mediated conditions
Methods of modulating heme oxygenase-1 expression and treating heme oxygenase-1 mediated conditions
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机译:调节血红素加氧酶-1表达和治疗血红素加氧酶-1介导的疾病的方法
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摘要
A method of modifying heme oxygenase-1 transcription is disclosed. The method includes modifying the nuclear concentration of biliverdin reductase, or fragments or variants thereof which bind to a heme oxygenase-1 regulatory sequence, in a cell, whereby an increase in the nuclear concentration of biliverdin reductase, or fragments or variants thereof, increases the transcription of heme oxygenase-1 and a decrease in the nuclear concentration of biliverdin reductase, or fragments or variants thereof, decreases the transcription of heme oxygenase-1.
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