EVALUATION METHOD OF MEMBRANE PERMEABILITY USING ARTIFICIAL MEMBRANE AND SCREENING METHOD OF MEMBRANE PERMEABILITY USING ARTIFICIAL MEMBRANE

摘要

PROBLEM TO BE SOLVED: To efficiently evaluate the lipid membrane permeability of a drug in a short time using an inexpensively producible synthetic high-molecular compound by employing a method more enhanced in the correlation with drug permeability in vivo than a conventional method without using complicated operation or calculation difficult to understand.;SOLUTION: A membrane permeability measuring method of a substance to be examined is characterized by using an artificial membrane containing a high-molecular compound with a molecular weight of 5,000-500,000 having a repeating unit represented by the formula (I).;COPYRIGHT: (C)2010,JPO&INPIT