THERMALLY RESPONSIVE POLYMER DERIVATIVE SIMULTANEOUSLY HAVING LOWER LIMIT CRITICAL TEMPERATURE AND UPPER LIMIT CRITICAL TEMPERATURE

摘要

PROBLEM TO BE SOLVED: To obtain a thermally responsive polymer which has an especially wide application area such as a drug delivery system (DDS), various separating agents, a catheter, an artificial muscle, and so on, and simultaneously has a lower limit critical temperature (LCST) and an upper limit critical temperature (UCST).;SOLUTION: The thermally responsive copolymer simultaneously has the lower limit critical temperature and the upper limit critical temperature, which is the thermally responsive copolymer containing a monomer component having a lower limit critical temperature and a monomer component having an upper limit critical temperature as copolymerization components, and is characterized in that the monomer component having the lower limit critical temperature is N-isopropyl acrylamide, and the monomer component having the upper limit critical temperature is N-acetyl acrylamide. Furthermore, the thermally responsive copolymer preferably contains a hydrophilic or hydrophobic monomer as a copolymerization component.;COPYRIGHT: (C)2009,JPO&INPIT