CONTRAST AGENTS COMPRISING METAL PARTICLES ENCAPSULATED IN MICROSPHERES FOR USE IN MEDICAL DIAGNOSTIC IMAGING AND THERAPY

摘要

The present invention relates to a composition that includes gadoliniumparticles encapsulated in microsphere shells. The composition is suitable foruse as a contrast agent with am plurality of imaging modalities, including,for example, ultrasound, magnetic resonance imaging, and computed temography.The compositions also also are useful for therapeutic applications, includingneutron capture therapy.