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TEST METHOD FOR PREDICTING RECURRENCE OF SOLID CANCER AND RECURRENCE PROPHYLACTIC

机译:预测固体癌复发率和复发率的试验方法

摘要

PPROBLEM TO BE SOLVED: To provide a cancer stem cell marker gene useful for diagnosing solid cancers, especially an initial stage or recurrence of breast cancer, a diagnostic tool for first occurrence or recurrence of solid cancer using such marker gene, and a prophylactic or a therapeutic agent for first occurrence or recurrence of solid cancer using such marker gene as a molecular target and a cancer stem cell as a target. PSOLUTION: The method for testing first occurrence or recurrence of solid cancer includes a step of measuring an expression level of a solid cancer stem cell marker gene in a biological sample collected from a test object by using a transcription product or translation product of the gene as an object. The prophylactic or therapeutic agent for first occurrence or recurrence of solid cancer includes a substance suppressing expression or activity of a solid cancer stem cell marker gene. The solid cancer stem cell marker gene is defined in the specification. PCOPYRIGHT: (C)2010,JPO&INPIT
机译:

要解决的问题:提供一种可用于诊断实体癌(尤其是乳腺癌的初始阶段或复发)的癌症干细胞标记基因,使用该标记基因的实体癌首次发生或复发的诊断工具以及以这样的标记基因为分子靶标并以癌干细胞为靶标的实体癌首次发生或复发的预防或治疗剂。

解决方案:测试实体癌的首次发生或复发的方法包括以下步骤:通过使用的转录产物或翻译产物测量从测试对象收集的生物样品中的实体癌干细胞标记基因的表达水平。以基因为对象。用于实体癌的首次发生或复发的预防或治疗剂包括抑制实体癌干细胞标记基因的表达或活性的物质。固体癌症干细胞标记基因在说明书中定义。

版权:(C)2010,日本特许厅&INPIT

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