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Compounds having selective activity for retinoid X receptors, and means for modulation of processes mediated by retinoid X receptors
Compounds having selective activity for retinoid X receptors, and means for modulation of processes mediated by retinoid X receptors
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机译:对类维生素A X受体具有选择性活性的化合物,以及调节类维生素A X受体介导的过程的手段
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摘要
Compounds, compositions, and methods for modulating processes mediated by Retinoid X Receptors using retinoid-like compounds which have activity selective for members of the subclass of Retinoid X Receptors (RXRs), in preference to members of the subclass of Retinoic Acid Receptors (RARs). Examples of such compounds are bicyclic benzyl, pyridinyl, thiophene, furanyl, pyrrole, and polyenoic acid derivatives including carbocyclic polyenoic acids. The disclosed methods employ compounds for modulating processes selectively mediated by Retinoid X Receptors.
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