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A DIRECTLY TABLETABLE GASTRORESISTANT SPHEROID AND METHOD FOR PREPARING THE SAME
A DIRECTLY TABLETABLE GASTRORESISTANT SPHEROID AND METHOD FOR PREPARING THE SAME
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机译:可直接食用的胃泌素类球体及其制备方法
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摘要
A directly tabletable gastroresistant spheroid, characterized in that it comprises: • a core comprising one or more active principles, and at least one binder directly coated with • a flexible and deformable film comprising an enteric polymer and a mixture of saturated and/or unsaturated polyglycosylated glycerides whose fatty acids contain at least 8 carbon atoms, • a water-dispersible outer layer comprising at least one disintegrant wherein said enteric polymer is present in proportions ranging up to 50% calculated by weight gain relative to the mass of the cores and the proportion of said mixture of saturated and/or unsaturated polyglycosylated glycerides is not more than 40% relative to the dry weight of polymer and wherein said spheroids has a diameter of between 0.1 and 2 mm.
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