首页> 外国专利> NOVEL RECOMBINANT 15-KDA POLYPEPTIDE AND USE OF SAME IN DETECTING HUMAN INFECTION WITH BARTONELLA HENSELAE

NOVEL RECOMBINANT 15-KDA POLYPEPTIDE AND USE OF SAME IN DETECTING HUMAN INFECTION WITH BARTONELLA HENSELAE

机译：重组15-KDA多肽的新方法及其在检测汉氏巴尔通体感染中的用途

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摘要

Disclosed are the cloning and expression of a novel antigen of Bartonella henselae. The recombinant polypeptide is found to be highly immunogenic and is useful as a diagnostic test antigen. The polypeptide of the present invention provides the basis of a diagnostic assay that is sensitive, rapid and accurate diagnosis of infection with Bartonella henselae using patient's sera. Disclosed also are the ELISA for both IgG and IgM and allows diagnosis of early and late infection.

机译：公开了一种汉氏巴尔通体的新抗原的克隆和表达。发现重组多肽是高度免疫原性的，并且可用作诊断测试抗原。本发明的多肽提供了诊断测定的基础，该诊断测定使用患者的血清灵敏，快速和准确地诊断了汉氏巴尔通体的感染。还公开了针对IgG和IgM的ELISA，并允许诊断早期和晚期感染。

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公开/公告号WO2010021846A2

专利类型
公开/公告日2010-02-25

原文格式PDF
申请/专利权人 MEDICAL DIAGNOSTIC LABORATORIES LLC;HOEY JOHN;HUANG LISA;ADELSON MARTIN;MORDECHAI ELI;
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申请/专利号WO2009US52921
发明设计人 HOEY JOHN;ADELSON MARTIN;MORDECHAI ELI;HUANG LISA;
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申请日2009-08-06
分类号C07K14/195;C12N15/31;C12N15/63;G01N33/569;
国家 WO
入库时间 2022-08-21 18:39:29

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