首页> 外国专利> COMPOSITION FOR DIAGNOSING HEPATOCELLUAR CARCINOMA USING RNPS1 OR H3F3A DIAGNOSIS MARKER AS AN DIAGNOSIS MARKER

COMPOSITION FOR DIAGNOSING HEPATOCELLUAR CARCINOMA USING RNPS1 OR H3F3A DIAGNOSIS MARKER AS AN DIAGNOSIS MARKER

机译:使用RNPS1或H3F3A诊断标志物作为诊断标志物诊断肝细胞癌的组合物

摘要

PURPOSE: A gene expression profile relating to HCC(hepatocellular carcinoma) early diagnosis and progress is provided to quickly diagnose hepatocellular carcinoma and screen anticancer drug.;CONSTITUTION: A composition for diagnosing hepatocellular carcinoma comprises a material measuring mRNA of RNPS1(RNA binding protein S1, serine-rich domain) or H3F3A(H3 histone, family 3A) and a material measuring protein level encoding the genes. The material measuring the gene at mRNA level is complementary sense, antisense primer, or probe. The material measuring the protein is antibody. A kit for diagnosing hepatocellular carcinoma comprises the composition. The measurement of the gene expression level is performed through RT-PCR(reverse transcriptase polymerase chain reaction).;COPYRIGHT KIPO 2010
机译:目的:提供一种与肝细胞癌(HCC)的早期诊断和进展有关的基因表达谱,以快速诊断肝细胞癌和筛选抗癌药物。;组成:一种诊断肝细胞癌的组合物,包括一种测量RNPS1(RNA结合蛋白S1)mRNA的物质。 ,富含丝氨酸的结构域)或H3F3A(H3组蛋白,家族3A)和测量编码该基因的蛋白质水平的物质。在mRNA水平上测量基因的材料是互补有义,反义引物或探针。测量蛋白质的物质是抗体。用于诊断肝细胞癌的试剂盒包含该组合物。基因表达水平的测定通过RT-PCR(逆转录聚合酶链反应)进行。; COPYRIGHT KIPO 2010

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