THE ESTIMATING METHOD OF THE ELASTICITY OF DNA TARGETING DRUG-BOUND DNA AND THE ESTIMATING METHOD OF THE DEGREE OF BINDING TO DNA USING THE AFOREMENTIONED METHOD

摘要

PURPOSE: a kind of DNA DNA targets that measurement elasticity combines to drug and method, the physical property for being provided to find DNA of the DNA and DNA target of combination degree to drug. ;CONSTITUTION: it is a kind of measure DNA elastic target medicine combine DNA be performed tension by measure and length and the combination of DNA. If the tension and length of a kind of measurement relationship by WLC there is change continuous pipe formula 3 to lack interelation kinks in the formula 1 of power length curve WLC models generates combination between. Tension appropriate and salinity are carried out in conjunction with target medicine and DNA. ;The 2010 of copyright KIPO submissions