Interaction site prediction apparatus, interaction site prediction method, program, and recording medium

摘要

It is intended to provide, for study of protein-protein interaction, an interaction site predicting apparatus, method of interaction site prediction, program and recording medium. Accordingly, a data base containing three-dimensional information and statistical information is created from information on known steric configurations of protein-protein complexes so as to enable analysis of protein-protein interaction. Further, with the use of this data base, there are accomplished with high precision prediction of the interaction site of protein in unknown steric configuration of protein-protein complex, prediction of the interaction site of protein whose steric configuration is unknown and prediction of relative positioning in the steric configuration of protein-protein complex. Still further, there are accomplished optimization of results of homology modeling of the steric configuration of multiple-chain protein and evaluation of alignment of the steric configuration of protein-protein complex for homology modeling.