首页> 外国专利> METHOD FOR ACQUIRING DEGREE OF METABOLIC DISORDER, METHOD FOR DETERMINING METABOLIC DISORDER, PROGRAM THEREFOR, DEVICE FOR ACQUIRING DEGREE OF METABOLIC DISORDER, AND DIAGNOSTIC PROGRAM BASED ON DETERMINATION OF METABOLIC DISORDER

METHOD FOR ACQUIRING DEGREE OF METABOLIC DISORDER, METHOD FOR DETERMINING METABOLIC DISORDER, PROGRAM THEREFOR, DEVICE FOR ACQUIRING DEGREE OF METABOLIC DISORDER, AND DIAGNOSTIC PROGRAM BASED ON DETERMINATION OF METABOLIC DISORDER

机译:基于代谢紊乱的确定度的方法,确定代谢紊乱的方法,程序,确定代谢紊乱的程度的装置以及基于确定代谢紊乱的诊断程序

摘要

PPROBLEM TO BE SOLVED: To provide a high-throughput acquiring method in acquiring a degree of disorder as the degree of separation from the reference value of the concentration of a metabolite in metabolome analysis or the like. PSOLUTION: At first, a predetermined metabolite becoming a measuring target is preset. Then, an plurality of metabolites in a test sample are separated by GC/MS and the concentration of each of the metabolites is acquired by mass analysis. On the basis of the logarithmic value of this concentration, a mean value Mean and standard deviation SD, the degree (n) of disorder is acquired. Herein, Mean and SD are the mean value of the concentration logarithmic values of the metabolite of a reference sample and standard deviation. By this constitution, the degree (n) of disorder is acquired with high-throughput and this degree (n) of disorder is used to determine the presence of metabolic disorder. PCOPYRIGHT: (C)2011,JPO&INPIT
机译:<解决的问题:提供一种高通量获取方法,用于获取代谢组分析等中与代谢物浓度的参考值的分离度作为分离度的无序度。

解决方案:首先,预设成为测量目标的预定代谢产物。然后,通过GC / MS分离测试样品中的多种代谢物,并通过质量分析获得每种代谢物的浓度。根据该浓度的对数值,平均值Mean和标准偏差SD,求出无序度(n)。在此,平均值和SD是参考样品的代谢物的浓度对数值的平均值和标准偏差。通过这种构造,以高通量获得疾病的程度(n),并且该疾病的程度(n)用于确定代谢疾病的存在。

版权:(C)2011,日本特许厅&INPIT

著录项

  • 公开/公告号JP2011085427A

    专利类型

  • 公开/公告日2011-04-28

    原文格式PDF

  • 申请/专利权人 KANAZAWA MEDICAL UNIV;

    申请/专利号JP20090236735

  • 发明设计人 HISAHARA TOMIKO;

    申请日2009-10-13

  • 分类号G01N27/62;G01N33/50;G01N33/68;

  • 国家 JP

  • 入库时间 2022-08-21 18:20:57

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