首页> 外国专利> Use Of Anti-Cancer Cell Composition For Treatment Of Head And Neck Cancer, Which Is Intended To Be Administered To Nutrient Artery Of Tumor

Use Of Anti-Cancer Cell Composition For Treatment Of Head And Neck Cancer, Which Is Intended To Be Administered To Nutrient Artery Of Tumor

机译:抗癌细胞组合物在治疗头颈部癌中的用途,所述头癌打算用于肿瘤的营养动脉

摘要

To provide a method of efficiently delivering cells having an anti-tumor activity to tumor tissues to evoke a stronger anti-tumor reaction, and a method of providing a more effective tumor regression effect, both in a cellular immunotherapy for cancer utilizing cells having an anti-tumor activity or antigen presenting cells for activating cells capable of exhibiting an anti-tumor activity. Provided are: a method of treating head and neck cancer, comprising administering an anti-cancer cell composition containing NKT cells activated in vitro with an NKT cell ligand into the tumor-feeding artery, and administering an NKT cell-stimulating agent containing antigen presenting cells treated with an NKT cell ligand through the upper respiratory tract mucous membrane; a use, in anti-cancer treatment of head and neck region, of the anti-cancer cell composition and the NKT cell-stimulating agent; a kit comprising the anti-cancer cell composition and the NKT cell-stimulating agent; and the anti-cancer cell composition.
机译:提供一种有效地将具有抗肿瘤活性的细胞传递到肿瘤组织以引起更强的抗肿瘤反应的方法,以及提供更有效的肿瘤消退作用的方法,在利用具有抗肿瘤活性的细胞进行的癌症细胞免疫疗法中-肿瘤活性或抗原呈递细胞用于激活能够表现出抗肿瘤活性的细胞。本发明提供一种治疗头颈部癌的方法,其包括将包含经NKT细胞配体体外活化的NKT细胞的抗癌细胞组合物施用于肿瘤供给动脉,以及施予包含抗原呈递细胞的NKT细胞刺激剂。通过上呼吸道粘膜用NKT细胞配体治疗;抗癌细胞组合物和NKT细胞刺激剂在头颈部抗癌治疗中的用途;包括抗癌细胞组合物和NKT细胞刺激剂的试剂盒;和抗癌细胞组成。

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