首页> 外国专利> VASCULAR ENDOTHELIAL PROGENITOR CELLS INTRODUCED WITH HAPTOGLOBIN GENE, AND COMPOSITION CONTAINING SAME FOR PROMOTING ANGIOGENESIS

VASCULAR ENDOTHELIAL PROGENITOR CELLS INTRODUCED WITH HAPTOGLOBIN GENE, AND COMPOSITION CONTAINING SAME FOR PROMOTING ANGIOGENESIS

机译:引入肝球蛋白基因的血管内皮祖细胞,其组成相同,可促进血管生成

摘要

The present invention relates to vascular endothelial progenitor cells introduced with a haptoglobin gene, and a composition containing the same for promoting angiogenesis, and more specifically, to vascular endothelial progenitor cells transformed with a recombinant vector containing a haptoglobin gene, a composition for promoting angiogenesis, containing the same as an active ingredient, and a method for promoting angiogenesis. The vascular endothelial progenitor cells transformed by the introduction of a haptoglobin gene according to the present invention is characterized in that the differentiation into mature vascular endothelial cells by haptoglobin expressed in cells is promoted, an activity for promoting angiogenesis is excellent, and vasculogenesis is also excellent, and thus can be useful for treating diseases caused by the preformation of blood vessels.
机译:本发明涉及导入有触珠蛋白基因的血管内皮祖细胞及其组合物,以促进血管生成,更具体地说,涉及用包含触珠蛋白基因的重组载体转化的血管内皮祖细胞,促进血管生成的组合物,含有作为有效成分的相同成分以及促进血管生成的方法。根据本发明,通过引入触珠蛋白基因转化的血管内皮祖细胞的特征在于,通过细胞中表达的触珠蛋白促进了向成熟血管内皮细胞的分化,促进血管生成的活性优异,并且血管生成也优异。 ,因此可用于治疗由血管形成引起的疾病。

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