DIAGNOSTIC MARKER OF ALZHEIMER'S DISEASE, SCREENING METHOD OF DRUG FOR PREVENTION AND TREATMENT OF ALZHEIMER'S DISEASE, AND DIAGNOSTIC METHOD OF ALZHEIMER'S DISEASE

摘要

PROBLEM TO BE SOLVED: To provide a novel diagnostic marker of Alzheimer's disease which is capable of diagnosing Alzheimer's disease accurately, in particular, even in an early stage before or after accumulation of Aβ in brain is started and is capable of diagnosing Alzheimer's disease easily and inexpensively.;SOLUTION: The diagnostic marker of Alzheimer's disease comprises amino acids or amino acid metabolites in blood or secretions of animals such as mammals. Blood or secretions available for the diagnostic marker include plasma, urine, and the like. The amino acids or amino acid metabolites include N,N-dimethyl glycine, sarcosine, serine, proline, hydroxyproline, valine, threonine, 2-hydroxypentanoate, 2-hydroxy-4-methyl pentanoate, alanine, isoleucine, phenylalanine, and the like.;COPYRIGHT: (C)2012,JPO&INPIT