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Method for screening a substance having an activity to improve the symptoms of non-human animal model and the mentally retarded mental retardation
Method for screening a substance having an activity to improve the symptoms of non-human animal model and the mentally retarded mental retardation
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机译:筛选具有改善非人类动物模型症状和弱智性智力障碍活性的物质的方法
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摘要
PROBLEM TO BE SOLVED: To provide a non-human model animal having mental retardation, and to provide a method for screening a substance having activity for improving mental retardation symptoms, using the model animal.;SOLUTION: The non-human model animal having mental retardation with PQBP-1 (polyglutamine tract binding protein-1) functions deleted is provided. The method for screening a substance, having the activity of ameliorating mental retardation symptoms using the model animal, is also provided.;COPYRIGHT: (C)2008,JPO&INPIT
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