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DEFERIPRONE FOR USE IN TREATING FRIEDREICH ATAXIA RESULTING FROM MITOCHONDRIAL IRON INDUCED DAMAGE IN THE ABSENCE OF GENERALISED IRON OVERLOAD
DEFERIPRONE FOR USE IN TREATING FRIEDREICH ATAXIA RESULTING FROM MITOCHONDRIAL IRON INDUCED DAMAGE IN THE ABSENCE OF GENERALISED IRON OVERLOAD
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机译:去铁酮在缺乏普遍铁超载的情况下用于治疗因线粒体铁引起的线粒体损伤
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摘要
A therapeutically effective amount of deferiprone or deferasirox or physiologically acceptable salts thereof for the prevention, stabilization, treatment, or reversal of iron-induced FRDA disease in patients resulting from mitochondrial iron-induced damage to preferentially reduce the iron stores in the mitochondria. Also for the treatment of other conditions affecting the brain where a key element in the generation of the resultant pathology is the intracellular mishandling of iron.
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