A method for the adaptive evolution of a cell and selection for a desired phenotype by serial propagation in an emulsion based system and uses thereof

摘要

The invention provides a method for the adaptive evolution of a cell and selection for a desired phenotype by serial propagation in an emulsion based system whereby said desired phenotype is optionally; a) selection for high yield/biomass production b) increased or decreased production of primary and/or secondary metabolites c) and/or increased or decreased levels of macromolecules and d) increased levels of (genetically engineered) biotechnologically relevant products, and/or two or more different organisms that interact with each other.