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PET radiopharmaceuticals for differential diagnosis of unilateral and bilateral state state of primary hyperaldosteronism
PET radiopharmaceuticals for differential diagnosis of unilateral and bilateral state state of primary hyperaldosteronism
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机译:PET放射药物可鉴别诊断原发性醛固酮增多症的单侧和双侧状态
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摘要
A step of introducing to a mammal having adrenal, selectively binds to CYP11B2 (aldosterone synthase) than (1) CYP11B1 (11β- hydroxylase) and CYP11B2 (aldosterone synthase) inhibitors radiolabeled ( including the step of performing positron emission tomography (PET) in the adrenal region in order to obtain functional PET images of 2) adrenal gland, the functional PET imaging methods for differential with unilateral adenoma and bilateral hyperplasia disclose. Furthermore, the radioactive tracer compounds suitable for use in this method, the precursor for making it, performed by one-pot reaction and rapid is also disclosed a method for manufacturing a can the radiotracer compound.
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