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Compositions and methods for the treatment and prevention of ulcerative colitis and colon cancer and screening methods to identify same
Compositions and methods for the treatment and prevention of ulcerative colitis and colon cancer and screening methods to identify same
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机译:用于治疗和预防溃疡性结肠炎和结肠癌的组合物和方法以及鉴定其的筛选方法
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摘要
The instant invention is based, at least in part, on the discovery that T-bet maintains host commensal relationships in the gastrointestinal tract. Accordingly, this invention provides methods of treating and/or preventing ulcerative colitis, and/or colon cancer, and/or preventing colonization of a subject's gastrointestinal tract with commensal bacteria that promote ulcerative colitis as well as methods of identifying agents that treat and prevent the same.
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