Bed and a groundwater remediation method with the increased content of iron and manganese ions and containing organic pollutants

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• 3. Nano-iron oxide suspension impregnated with activated carbon for the in situ adsorption and enrichment of organic pollutants and their increased biological degradation in contaminated groundwater [P] . 德国专利： DE202018005449U1 . 2020.02.27
• 4. METHOD OF REMEDIATION OF CONTAMINATED GROUNDWATER AND CONTAMINATED BED AND REMEDIATION SYSTEM [P] . 日本专利： JP2000176487A . 2000-06-27

  机译： 污染地下水和被污染床的修复方法及修复系统

• 5. Nano-iron oxide suspension impregnated with activated carbon for the in situ adsorption and enrichment of organic pollutants and their enhanced biodegradation in contaminated groundwater [P] . 德国专利： DE202018005449U1 . 2020-04-09

  机译： 活性炭浸渍的纳米氧化铁悬浮液，用于原位吸附和富集有机污染物及其在被污染的地下水中的生物降解作用

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• 1. BACKGROUND： Vibrio vulnifi cus inside the body could activate the NF-!B signaling pathwayand initiate the inflammatory cascade. The lung is one of the earliest organs affected by sepsisassociated with acute lung injury. High mobility group protein B1 （HMGB1） is an important late-actingpro-infl ammatory cytokine involving in the pathophysiology of sepsis. It is also involved in the injuryprocess in the lung, liver and intestine. There has been no report on the involvement of HMGB1 inVibrio vulnifi cus sepsis-induced lung injury.METHODS： Sixty rats were randomly divided into a normal control group （group A, n=10） anda Vibrio vulnificus sepsis group （group B, n=50）. Sepsis was induced in the rats by subcutaneousinjection of Vibrio vulnificus （concentration 6×108 cfu/mL, volume 0.1 mL/100g）） into the left lowerlimbs. The rats in group B were sacrifi ced separately 1, 6, 12, 24, and 48 hours after the infection.Their lungs were stored as specimens, lung water content was measured, and lung pathology wasobserved under a light microscope. The expressions of the HMGB1 gene and protein in the lungswere detected by RT-PCR and Western blot. Data were analyzed with one-way analysis of variance（ANOVA） and the LSD method for pair-wise comparison between the two groups. P〈0.05 wasconsidered statistically signifi cant.RESULTS： Compared to group A （0.652±0.177）, HMGB1 mRNA expression in the lungs ofgroup B was signifi cantly higher at 0 hour （1.161±0.358, P=0.013）, 24 hours （1.679±0.235, P=0.000）,and 48 hours （1.258±0.274, P=0.004） （P〈0.05）, and peaked at 24 hours. Compared to group A（0.594±0.190）, HMGB1 protein expression at 6 hours （1.408±0.567, P=0.026） after infection wassignificantly increased （P〈0. 05）, and peaked at 24 hours （2.415±1.064, P=0.000） after infection.Compared to group A （0.699±0.054）, lung water content was significantly increased at 6 hours（0.759±0.030, P=0.001）,12 hours （0.767±0.023, P=0.000）, 24 hours （0.771±0.043, P=0.000） and 48hours （0.789±0.137, P=0.000） after infection （P〈0.05）. Compared to group A, pathological changesat 12 hours in group B indicate marked pulmonary vascular congestion, interstitial edema andinfl ammatory infi ltration. Alveolar cavity collapse and boundaries of the alveolar septum could not beclearly identifi ed.CONCLUSION： Vibrio vulnifi cus sepsis can lead to injury in rat lungs, and increased HMGB1expression in lung tissue may be one of the mechanisms for injury from Vibrio vulnifi cus sepsis. [J] . Qiao-meng Qiu ,Zhong-wang Li ,Lu-ming Tang . 世界急诊医学杂志(英文) . 2011,第4期
• 2. Manganese extraction from high-iron-content manganese oxide ores by selective reduction roasting-acid leaching process using black charcoal as reductant [J] . 张元波 ,赵熠 ,游志雄 . 中南大学学报 . 2015,第007期
• 3. Removing Iron Ions Contaminants from Groundwater Using Modified Nano-Hydroxyapatite by Nano Manganese Oxide [J] . Mohammed Abd-El-Aal Ahmed Ayash ,Tarek Ahmed Seaf Elnasr ,Madiha Hassan Soliman . 水资源与保护（英文） . 2019,第6期
• 4. 地下水中含有铁·锰·氨氮的超高速生物处理 [C] . 林野 ,宫本岳志 ,蔡惠良 . 第11届中日供水技术国际交流会 . 2011
• 5. 四氧化三铁激活过硫酸钠降解地下水中有机污染物的研究 [A] . 张丽娜 . 2017