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Pentacyclic triterpenes for use in the prevention or treatment of acute or subacute myocarditis

机译:五环三萜类化合物,用于预防或治疗急性或亚急性心肌炎

摘要

The use of a pentacyclic triterpene in the production of a pharmaceutical or neutraceutical composition to prevent or to treat a myocardial inflammatory disease, preferably acute or subacute myocarditis, to prevent or to treat a disease involving the appearance of calcium-salt deposits, and to prevent or to treat a disease involving fibrotic accumulation. Preferably, said pentacyclic triterpene is oleanolic acid. The invention further relates to a pharmaceutical or neutraceutical composition that comprises a triterpene in conjunction with at least one pharmaceutically acceptable adjuvant and/or vehicle or, when the composition is neutraceutical, a neutraceutically acceptable adjuvant and/or vehicle, for treating or preventing a myocardial inflammatory disease, preferably acute or subacute myocarditis, for preventing or treating a disease involving the appearance of calcium-salt deposits, and for preventing or treating a disease involving fibrotic accumulation. Preferably, said pentacyclic triterpene is oleanolic acid.
机译:五环三萜在制备药物或中性神经营养药物组合物中的用途,以预防或治疗心肌炎性疾病,优选急性或亚急性心肌炎,预防或治疗涉及钙盐沉积物出现的疾病,以及预防或治疗涉及纤维化累积的疾病。优选地,所述五环三萜是齐墩果酸。本发明进一步涉及包含三萜与至少一种药学上可接受的佐剂和/或赋形剂结合的药物或神经营养药物组合物,或者当所述组合物是神经营养剂时,其是用于治疗或预防心肌的药物或神经营养药物组合物。炎性疾病,优选急性或亚急性心肌炎,用于预防或治疗涉及钙盐沉积物出现的疾病,以及用于预防或治疗涉及纤维化积聚的疾病。优选地,所述五环三萜是齐墩果酸。

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