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AGGREGATE PARTICLES COMPRISING NANOPARTICULATE DRUG PARTICLES OF UMECLIDINIUM BROMIDE, VILANTEROL TRIFENATATE AND FLUTICASONE FUROATE
AGGREGATE PARTICLES COMPRISING NANOPARTICULATE DRUG PARTICLES OF UMECLIDINIUM BROMIDE, VILANTEROL TRIFENATATE AND FLUTICASONE FUROATE
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机译:包含毫微溴化铵,三氟萘酸三氟萘酸酯和糠酸氟替卡松的纳米颗粒药物颗粒的聚集颗粒
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摘要
The present invention relates to aggregate particles comprising nanoparticulate drug particles. In particular, the present invention is directed to aggregate particles comprising nanoparticulate drug particles of umeclidinium bromide and optionally vilanterol trifenatate and/or fluticasone furoate. Aggregate particles of the present invention may further comprise nanoparticulate excipient particles and one or more binders. The invention also relates to powder compositions suitable for inhalation that comprise said aggregate particles, processes of producing said aggregate particles, and use of said powder compositions in the treatment of respiratory diseases, such as asthma and COPD.
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