Preparation of composite particles comprised of antifungal drug and new additive agent for dry powder inhalation by crystallization during spray drying

摘要

The remarkable advancement of antifungal drugs has many infectious diseases overcome. The emerging infectious disease named as a new strain of influenza has appeared and resistant strain such as Methicillin-Resistant Staphylococcus Aureus (MRSA) and Multiple-Drug-Resistant Pseudomonas aeruginosa (MDRP) has increased. There remains unanswered with regard to increasing MRSA and MDRP. We should find out a new approach to solve out these remaing prolblems since the development of new antifungal drugs is extremely difficult. Some applications of pharmaceutical technology has been just attemptted to develop the new technology, which is more effective and safer compared to existing antifungal drugs.