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Methods for in vitro differentiation of neural stem cells, motor neurons and dopamine neurons from primate embryonic stem cells
Methods for in vitro differentiation of neural stem cells, motor neurons and dopamine neurons from primate embryonic stem cells
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机译：从灵长类胚胎干细胞体外分化神经干细胞，运动神经元和多巴胺神经元的方法
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摘要
A method of differentiating embryonic stem cells into neural and motor cells is disclosed. In one embodiment, the invention comprises culturing a population of cells comprising a majority of cells that are characterized by an early rosette morphology and are Sox1-/Pax6+ in the presence of FGF2, FGF4, FGF8, FGF9, or RA wherein the cells are characterized by an neural tube-like rosette morphology and are Pax6+/Sox1+.
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