Composition based on polu00cdmero bioadesivo and at least a photosensitiser, class of ftalocianinas, its process of obtaining and its applications in therapy fotodinu00c2micas

摘要

Composition based polu00cdmero bioadesivo and at least a photosensitiser, class of ftalocianinas, its process of obtaining and its applications in therapy fotodinu00c2micas.The present invention is a composition based on the association between at least one substance photosensitiser (FS) class of ftalocianinas and at least a polymer bioadesivo, mainly the PVM / MA [poly (methyl vinyl ether co carbon malu00e9ico)], which presents itself in a form The solubilizada or nano or micro particles.This composition is useful in preparing medicine for photodynamic therapy for the treatment of neoplastic and pre neoplastic lesions, as well as for photodynamic therapy for the treatment of microbial infections, such as, for example, the fungal and bacterial.One aspect of the invention is the process of obtaining the composition, since it is based on the combination of FS class of ftalocianinas polymers bioadesivos, are these in the form of nano or micro particles or solubilized.This combination allows to obtain advantageous characteristics such as bioadesividade, transport, selectivity to the target tissue / cell and photodynamic activity in aqueous media are these biological or not.Another aspect of the present invention refers to the use of the composition as agents of FS in processes fotodinu00e2micos for elimination or reduction of microbial load in any materials, biological or not.