PHARMACEUTICAL COMPOSITION COMPRISING, AS ACTIVE INGREDIENTS, PEPTIDES WHICH EXHIBIT INHIBITORY ACTIVITY AGAINST ANGIOTENSIN-I CONVERTING ENZYME FOR PREVENTING OR TREATING CARDIOVASCULAR DISEASES

摘要

The present invention relates to peptides which are separated from the fractions of oyster enzyme hydrolysate and which exhibit inhibitory activity against angiotensin-converting enzyme (ACE), and to a pharmaceutical composition comprising the peptides as active ingredients for preventing or treating cardiovascular diseases. More particularly, the peptides of the present invention separated from the fractions of oyster enzyme hydrolysate may significantly inhibit the activity of ACE, and may exhibit the effects of blood pressure regulation and hypertension prevention. Therefore, the fractions of oyster enzyme hydrolysate or peptides separated therefrom can be effectively used as active ingredients for a pharmaceutical composition for preventing or treating cardiovascular diseases.