首页> 外国专利> Pharmaceutical composition containing Peptide with angiotensin-I Converting Enzyme inhibitory activity for preventing or treating cardiovascular disease

Pharmaceutical composition containing Peptide with angiotensin-I Converting Enzyme inhibitory activity for preventing or treating cardiovascular disease

机译:包含具有血管紧张素-I转换酶抑制活性的肽的药物组合物,用于预防或治疗心血管疾病

摘要

The present invention relates to a peptide having an inhibitory effect on an angiotensin converting enzyme (ACE) isolated from a fraction of oyster enzyme hydrate and a pharmaceutical composition for preventing or treating cardiovascular diseases containing the peptide as an active ingredient Specifically, the peptide isolated from the fraction of oyster hydrolyzate of the present invention specifically inhibits ACE activity, exhibits an effective blood pressure-controlling effect and a hypertension-preventing effect, and thus the fractions of the oyster enzyme hydrolyzate Or peptides derived therefrom may be usefully used as an active ingredient of a pharmaceutical composition for the prevention or treatment of cardiovascular diseases.
机译:本发明涉及对从一部分牡蛎酶水合物分离出的血管紧张素转换酶(ACE)具有抑制作用的肽,以及以该肽为有效成分的预防或治疗心血管疾病的药物组合物。本发明的牡蛎水解产物的馏分特异性地抑制ACE活性,显示出有效的血压控制作用和高血压预防作用,因此,牡蛎酶水解产物的馏分或由其衍生的肽可以有效地用作活性成分。用于预防或治疗心血管疾病的药物组合物。

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