STRAIN OF INFLUENZA VIRUS A/17/VICTORIA/2011/89 (H3N2) FOR PRODUCTION OF LIVE INFLUENZA INTRANASAL VACCINE FOR ADULTS AND CHILDREN

摘要

FIELD: biotechnology.;SUBSTANCE: strain A/17/Victoria/2011/89 (H3N2) propagates actively in developing chicken embryos at the optimum temperature of 32°C. It is characterised by temperature-sensitivity and cold-adaptiveness. The reassortant inherited genes encoding the surface antigens of virus of haemagglutinin (HA) and neuraminidase (NA), from the epidemic parental virus and other six genes encoding internal non-glycated proteins from attenuation donor. The strain is deposited in the State Collection of viruses FSBI "Research Institute of Virology n.a. DI Ivanovsky" under the number 2724.;EFFECT: invention can be used in practical healthcare for prevention of seasonal influenza morbidity among adults and children, using live influenza intranasal vaccine from the said strain.;1 dwg, 6 tbl