首页> 外国专利> Detecting natural or synthetic cells e.g. de novo programmed cells to organism-crisis situation activity imitative input-output transformation, comprises performing cellular reaction upon contact with mixture of e.g. folic acid, vitamin B12

Detecting natural or synthetic cells e.g. de novo programmed cells to organism-crisis situation activity imitative input-output transformation, comprises performing cellular reaction upon contact with mixture of e.g. folic acid, vitamin B12

机译:检测天然或合成细胞,例如从头编程的细胞向生物危机情况活动的模拟输入-输出转化,包括与例如乙醛的混合物接触后进行细胞反应。叶酸,维生素B12

摘要

Detecting natural or synthetic, proliferative cells which are genetically programmed or de novo programmed for function of an organism-crisis situation activity imitative input-output transformation, comprises carrying out a cellular reaction with respect to organism-crisis situation activity, upon contact with a single product mixture of the products of iron(II) sulfate, folic acid and vitamin B12. The genetic programming of the function of each organism-crisis situation activity is the genetic information of e.g. heat shock 70kDa protein 1B gene and mitofusin-2 gene. Detecting natural or synthetic, proliferative cells which are genetically programmed or de novo programmed for function of an organism-crisis situation activity imitative input-output transformation, comprises carrying out a cellular reaction with respect to organism-crisis situation activity, upon contact with a single product mixture of the products of iron(II) sulfate, folic acid and vitamin B12 (cyanocobalamin). The genetic programming of the function of each organism-crisis situation activity is the genetic information of heat shock 70kDa protein 1B gene (HSPA1B), mitofusin-2 gene (MFN2), ATP-binding cassette sub-family-B member-7 gene (ABCB7), methylenetetrahydrofolate reductase gene (MTHFR), methylmalonic aciduria type-A gene (MMAA) and methylmalonic aciduria and homocystinuria type-C gene (MMACHC) in the cells. The single input of the cellular contact with a single-product mixture as a member of a product mixture library transforms into an output of the cellular response in the form of a change in the expression of the genes HSPA1B, MFN2, ABCB7, MTHFR, MMAA and MMACHC.
机译:检测经过遗传编程或从头编程的天然或合成增殖细胞,以实现生物危机情况活动的模仿输入-输出转换功能,包括在与单个生物接触后针对生物危机情况活动进行细胞反应硫酸铁(II),叶酸和维生素B12的产品混合物。每个生物危机情况活动的功能的遗传程序设计是例如热激70kDa蛋白1B基因和mitofusin-2基因。检测经过遗传编程或从头编程的天然或合成增殖细胞,以实现生物危机情况活动的模仿输入-输出转换功能,包括在与单个生物接触后针对生物危机情况活动进行细胞反应硫酸铁(II),叶酸和维生素B12(氰钴胺)的产物的混合物。每种生物危机情况活动的功能的遗传程序设计是热休克70kDa蛋白1B基因(HSPA1B),线粒体2基因(MFN2),ATP结合盒亚家族B成员7基因( ABCB7),亚甲基四氢叶酸还原酶基因(MTHFR),甲基丙二酸尿症A型基因(MMAA)和甲基丙二酸尿症和C型高半胱氨酸尿症基因(MMACHC)。与单一产物混合物作为产物混合物库成员的细胞接触的单一输入以基因HSPA1B,MFN2,ABCB7,MTHFR,MMAA的表达变化的形式转化为细胞应答的输出和MMACHC。

著录项

  • 公开/公告号DE102013010253B3

    专利类型

  • 公开/公告日2014-02-06

    原文格式PDF

  • 申请/专利权人 KIEFER HEINZ;

    申请/专利号DE20131010253

  • 发明设计人 KIEFER HEINZ;

    申请日2013-06-18

  • 分类号C12Q1/02;

  • 国家 DE

  • 入库时间 2022-08-21 15:37:24

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