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IDENTIFYING TARGET PATIENTS FOR NEW DRUGS BY MINING REAL-WORLD EVIDENCE

机译:通过挖掘真实证据来确定新药的目标患者

摘要

Systems and methods for patient identification include identifying a set of mature drugs similar to a target drug using a processor based on a drug similarity measure. A plurality of outcome models are constructed for each mature drug in the set based on real-world evidence, the plurality of outcome models representing a patient response to each mature drug. A patient response to the target drug is predicted based on the outcome models to identify patients for the target drug.
机译:用于患者识别的系统和方法包括使用基于药物相似性度量的处理器识别与目标药物相似的一组成熟药物。基于现实世界的证据,为该组中的每种成熟药物构建了多个结果模型,该多个结果模型代表患者对每种成熟药物的反应。基于结果模型预测患者对靶标药物的反应,以识别靶标药物的患者。

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