首页> 外国专利> Method of treating diabetic peripheral neuropathy through amendment of pre-neuronal diabetic coagulative micro-angiopathy and neuronal deficiency of mitochondrial ATP production, and through induction of neuronal regeneration

Method of treating diabetic peripheral neuropathy through amendment of pre-neuronal diabetic coagulative micro-angiopathy and neuronal deficiency of mitochondrial ATP production, and through induction of neuronal regeneration

机译:通过改善神经元前糖尿病性凝血微血管病和线粒体ATP产生的神经元缺乏,并诱导神经元再生来治疗糖尿病周围神经病变的方法

摘要

DPN is an intractable and tormenting neurovascular and dermal disorder.;Two patients of DPN of stocking-glove pattern were treated with SAG for treatment of microvascuar coagulopathy, induction of vasodilation and possible induction of angioneogenesis; with ALC for ATP generation through mitochondrial beta-oxidation of fats; and with ALA for antioxidative stress to prevent precipitation of vascular damage and to prevent DPN recurrence. SAG+ALC was to cure maceration.;Thus, SAG+ALC+ALA was effective in mitigating and curing their distresses. It shall be one of the logical and practical means of prompt DPN therapy not only to alleviate DPN but also to lead to “cure.”
机译:DPN是一种难治且折磨的神经血管和皮肤疾病。; 2例穿手套型DPN的患者接受了SAG治疗,以治疗微血管凝血病,诱导血管舒张并可能诱导血管生成。用ALC通过脂肪的线粒体β-氧化产生ATP;并与ALA一起使用以抗氧化应激,以防止血管损伤沉淀并防止DPN复发。 SAG + ALC可以治愈浸渍。因此,SAG + ALC + ALA可以有效缓解和缓解痛苦。这不仅是减轻DPN的方法,而且还可以导致“治愈”,这是及时DPN治疗的逻辑和实际手段之一。

著录项

  • 公开/公告号US2014371280A1

    专利类型

  • 公开/公告日2014-12-18

    原文格式PDF

  • 申请/专利权人 SHINICHI OKUYAMA;JESSI LU;

    申请/专利号US201413999635

  • 发明设计人 JESSI LU;SHINICHI OKUYAMA;

    申请日2014-03-14

  • 分类号A61K31/426;A61K31/221;A61K31/216;

  • 国家 US

  • 入库时间 2022-08-21 15:23:30

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