首页> 外国专利> Bcl-2 protein expressing agent, apoptosis inhibiting agent, and agent for preventing ultraviolet damage to dns of an epidermal cell

Bcl-2 protein expressing agent, apoptosis inhibiting agent, and agent for preventing ultraviolet damage to dns of an epidermal cell

机译:Bcl-2蛋白表达剂,细胞凋亡抑制剂和紫外线对表皮细胞dns的损害

摘要

An object of the present invention is to provide an apoptosis inhibiting agent which inhibits apoptosis of a cell having a DNA which is directly or indirectly damaged with ultraviolet-rays or the like, enhances the tissue restoring property of a cell, can be added to various drugs, and can be expected to be widely applied. An apoptosis inhibiting agent for an epidermal cell, containing a water and ethanol-soluble glycyrrhiza extract as an active ingredient. The apoptosis inhibiting agent has an anti-apoptotic factor due to expression of BLC-2 protein, and has the property of preventing a DNA damage due to ultraviolet-rays. The agent alleviates the DNA damage of an epidermal cell due to ultraviolet exposure and, moreover, does not abnormally or adversely affect a normal skin cell.
机译:本发明的目的是提供一种凋亡抑制剂,其可以抑制具有被紫外线等直接或间接破坏的DNA的细胞的凋亡,增强细胞的组织恢复特性,并且可以添加到各种细胞中。药物,有望被广泛应用。用于表皮细胞的凋亡抑制剂,其包含水和乙醇可溶的甘草提取物作为活性成分。凋亡抑制剂由于BLC-2蛋白的表达而具有抗凋亡因子,并且具有防止由于紫外线引起的DNA损伤的性质。该试剂减轻了由于紫外线暴露引起的表皮细胞的DNA损伤,而且不会对正常皮肤细胞产生异常或不利影响。

著录项

  • 公开/公告号BRPI0822678A2

    专利类型

  • 公开/公告日2015-06-30

    原文格式PDF

  • 申请/专利权人 NISHIHARA CO. LTDA;

    申请/专利号BR2008PI22678

  • 发明设计人 MASAO TAKITA;

    申请日2008-05-23

  • 分类号A61K36/48;A61K8/97;A61Q19/06;

  • 国家 BR

  • 入库时间 2022-08-21 15:16:04

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