Method of inhibition of angiogenesis in a person in need including administration of an antibody associated withthe extracellular region of the human magic mill (MRI) in the individual. Substance having the amino acid sequences (i) to (iii)(i v) to (v i) or (i) to (vi) amino acid sequences: (i) S S S S S V S S Y (ii) L T S N L A S iii) Q Q W S N P L T iv) D Y N L N N v)V I N P N Y T S S N K K G (vi) G R D Y Y F G Y. Method of inhibitionangiogenesis in a person in need including administration of the extracellular sector (residue 1-467) of the MRI or a fragment thereof that inhibits angiogenesis to the person. Method of suspension afterinhibition and/or proliferation of endothelial cells including administration of the extracellular sector of the MRI or a fragment thereof that inhibits migration and/or endothelial cell proliferation.
展开▼
