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Compounds and pharmaceutical compositions for treating disorders associated with the 5-HT 1A and 5-HT 2A receptors

机译:用于治疗与5-HT 1A和5-HT 2A受体相关的疾病的化合物和药物组合物

摘要

This invention is related to the alkyl-piperazine-phenyl 4 (3H)-quinazolinones general formula (I) compounds, pharmacologically active and able to act on the 5-HT1A and 5-HT2A serotonin receptors in a manner that promotes the control, relief or cure of disorders associated with these receptors, and pharmaceutical compositions containing the compounds for the treatment of disorders associated with these receptors. These compounds and their pharmaceutical compositions are useful in the treatment of conditions such as depression, anxiety, phobias, addictions, aggressiveness, impulsiveness, panic, psychotic, eating and sleep disorders, obsessive-compulsive disorder and female sexual dysfunctions, among other disorders associated with these receptors.
机译:本发明涉及烷基-哌嗪-苯基4(3H)-喹唑啉酮类通式(I)化合物,其药理活性并且能够以促进控制,缓解的方式作用于5-HT1A和5-HT2A5-羟色胺受体。或与这些受体有关的疾病的治疗,以及含有用于治疗与这些受体有关的疾病的化合物的药物组合物。这些化合物及其药物组合物可用于治疗诸如抑郁,焦虑,恐惧症,成瘾,攻击性,冲动性,恐慌,精神病,进食和睡眠障碍,强迫症和女性性功能障碍等疾病,例如与以下有关的疾病:这些受体。

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