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MALE TESTOSTERONE TITRATION METHODS, INTRANASAL TESTOSTERONE BIO-ADHESIVE GEL FORMULATIONS AND TREATMENT OF HYPOGONADISM AND TRT
MALE TESTOSTERONE TITRATION METHODS, INTRANASAL TESTOSTERONE BIO-ADHESIVE GEL FORMULATIONS AND TREATMENT OF HYPOGONADISM AND TRT
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机译:男性睾丸激素滴定方法,鼻内睾丸激素生物胶凝制剂和低血糖症和TRT的治疗
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摘要
The present invention relates to pernasal testosterone bio-adhesive gel formulations for intranasal administration and testosterone replacement treatment methods for using the pernasal testosterone bio-adhesive gel formulations for providing sustained intranasal delivery of testosterone to testosterone deficient males to treat, for example, male subjects diagnosed with hypogonadism. The present invention is also concerned with a novel titration method to determine the appropriate daily treatment regimen, i.e., a BID or TID treatment regimen, to administer the intranasal gels of the present invention to treat hypogonadism or TRT.
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