Methods and test specimens for the detection of isoniazid sensitivity in Mycobacterium tuberculosis

摘要

According to this invention, new expedient in order to detect more securely whether or not INH sensitivity of the tubercle bacillus, namely, the tubercle bacillus is the INH tolerance germ, is offered. The method of detecting the isoniajido sensitivity in the tubercle bacillus of this invention includes the process which detects the mutation which participates in isoniajido tolerance process, and the said the fabG1 gene of the tubercle bacillus in the inspection body is acquired concerning the fabG1 gene which is acquired. Method of this invention may include the process which detects the mutation of the furA gene of the tubercle bacillus according to need, desirably, combining with other known isoniajido sensitivity method of detection is good.