Using small molecules to improve the performance of Mafia in pancreatic endocrine pictograph

摘要

This application provides methods, Cell Culture and differentiation Media for Promoting the differentiation of Pluripotent Stem Cells into pancreatic Endocrine cells of a mature phenotype. Pancreatic Endocrine cells express insulin Hormone from simple, Pdx1 and Mafa (, nkx6.1 fibrosarcoma Oncogene homologue of the Avian Muscle aponeurotic (MAF).In one or more stages of Differentiation, the Crop can be grown in a container at the Air Liquid interface.