Baculovirus expression vector, insect cells comprising said vector, use of said vector for preparing an immunogenic Salmonid Aplha Virus like particle, and vaccine comprising said virus like particle for treatment of Salomonid Alpha Virus infection

摘要

The present invention relates to Salmonid Alphavirus (SAV) virus-like particles (VLP's), to their use as a medicament, to baculovirus expression vectors comprising a polynucleotide encoding the SAV E2 protein and insect cells comprising such expression vectors , to the use of baculovirus based expression systems for the production of SAV VLP's, to methods for the production of SAV VLP's, and to vaccines comprising such SAV VLP's.