Treatment of heart failure with normal ejection fraction

摘要

The disclosure relates to a use of perhexiline, or a pharmaceutically acceptable salt thereof, in the manufacture of a medicament for use in a method of treating heart failure in a subject in need thereof, wherein the subject has (i) disordered passive filling of the left ventricle, (ii) a normal left ventricular ejection fraction, and (iii) one or more symptoms of chronic heart failure