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EPIGENETIC ENGINEERING TO STUDY THE ROLE OF ABERRANT DNA METHYLATION IN DISEASE
EPIGENETIC ENGINEERING TO STUDY THE ROLE OF ABERRANT DNA METHYLATION IN DISEASE
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机译:表观遗传工程研究异常DNA甲基化在疾病中的作用
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摘要
Embodiments of the disclosure concern compositions and methods for genetic engineering related to hypermethylation of sequences. In particular embodiments, there are methods and compositions to induce DNA methylation in a manner that leads to transcriptional suppression of a target gene that allows characterization of the gene and/or its expression.
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