METHOD FOR INCREASING THE EFFECTIVENESS OF TREATMENT WITH AN ANTIDEPRESSANT IN COMPLEX ANTIDEPRESSIVE TREATMENT, AND PHARMACEUTICAL COMBINATION

摘要

The invention is based on the use of acetyl-L-carnitine (ALC) as a means for increasing the effectiveness of antidepressive treatment and can be used in a clinic in antidepressive treatment with non-natural antidepressants, such as agomelatine, venlafaxine and fluvoxamine, for treating depressive disorders relating to various depressive episodes, in particular depressive episodes when suffering from bipolar affective disorder or from a recurrent depressive disorder, in patients in late adulthood, including in patients older than 60.