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CD154 Antibody to specific primates CD154 and hybridoma cell producing the same

机译:特定灵长类动物CD154的CD154抗体和产生该抗体的杂交瘤细胞

摘要

The present invention relates to an anti-monkey CD154 antibody specifically bonded to a monkey CD154 antigen, and relates to a fusion cell strain for producing the antibody. According to the present invention, the CD154-expressed cells of the primates, particularly human and monkeys can be detected by using the anti-monkey CD154 antibody. The anti-monkey CD154 antibody can be used as an immunosuppressive drug and an agent for treating associated diseases, by blocking the signal delivery of CD40-CD40L(CD40 ligand, CD154).
机译:本发明涉及与猴CD154抗原特异性结合的抗猴CD154抗体,并且涉及用于产生该抗体的融合细胞株。根据本发明,可以通过使用抗猴CD154抗体来检测灵长类,特别是人和猴的CD154表达细胞。通过阻断CD40-CD40L(CD40配体,CD154)的信号传递,抗猴CD154抗体可以用作免疫抑制药物和治疗相关疾病的药物。

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