Antibodies against CD154 whose variable domain of the heavy chain has CDR1 and CDr3 specific sequence of DNA that encodes, Pharmaceutical composition containing such Antibodies,Useful for treating Diseases mediated by CD154, as the rejection of allografts.

摘要

Provides a link of CD154 Molecule, in particular an Antibody to human CD154, especially a Human Antibody to human CD154,Where the CDRs of amino acids as defined,To be used and the Treatment or prevention of diseases or Disorders where it is therapeutically beneficial Modulation, and / or interference with,Cd154o inhibition of CD40 CD154 interactions;.