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READING INDUCTOR AND THERAPEUTIC AGENT FOR GENETIC DISEASES, CAUSED BY MUTATIONS OF NONSENSE-MUTATION TYPE

机译:感应突变类型突变导致的遗传疾病阅读诱导剂和治疗剂

摘要

FIELD: chemistry.SUBSTANCE: claimed is group of the inventions, relates to application of compound of structural formula(arbecacin)as reading inductor for induction of reading of premature stop-codon, formed as a result of nonsense-mutations, and to medication, including said inductor, for treatment of genetic disease, caused by nonsense-mutations (for instance, Duchenne muscular dystrophy).EFFECT: realisation of the claimed purpose.4 cl, 10 dwg, 4 tbl
机译:技术领域本发明的组,涉及结构式化合物(阿贝卡星)作为阅读诱导剂的应用,用于诱导由无义突变形成的过早终止密码子的阅读,以及药物,包括:上述诱导剂,用于治疗由无义突变(例如,杜兴氏肌营养不良症)引起的遗传疾病。效果:实现了所要求的目的。4cl,10 dwg,4 tbl

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